Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p42 | Bone biomechanics and quality | ECTS2016

Sexually dimorphic response on bone development after neonatal thymectomy in rats

de Mello Wagner Garcez , Kiill Noelle Egidia Watanabe , Kayahara Gisele Mitsui , Nascimento Olivia Borghi , Marqui Narayana Guimaraes , Crivelini Marcelo Macedo , Louzada Mario Jefferson Quirino , Antunes-Rodrigues Jose , de Castro Joao Cesar Bedran

The effects of neonatal thymectomy, at 3 days of age, on skeletal sexual dimorphism and bone quality during the development were examined in male and female Wistar rats. Rats were euthanized at 20, 40, or 120 postnatal days and femurs were collected. The Biomechanical compression test was used to evaluate bone breaking strength, energy-to-fracture, and extrinsic stiffness. During the prepubertal period, the neonatal thymectomy increases extrinsic stiffness of bone tissue signi...